Hunt Slonem is primarily a painter focused on naturalistic subject matter with an emphasis on bright color. His reference to the mystical is prevalent as his work pivots between the fantastic and the natural; these natural forms ultimately become the subjects for many of his artworks. Repetition is also a prominent aspect of his work, to Hunt they are a reference to Andy Warhol however the true nature of his repetition is a spiritual practice, a worship.
As an artist, he endeavors to explore the many expressive faculties of color, his paintings are rich, layered with thick brushstrokes of vivid color. Since his first solo show at Fischbach Gallery in 1977, his works have joined the permanent collections of museums including the Solomon R. Guggenheim Museum, the Metropolitan Museum of Art, the Whitney, the Smithsonian American Art Museum, the Würth Museum, the Miro Foundation, and the New Orleans Museum of Art.